CYP
약물상호작용 |
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Base material |
CYP450
분자체 |
대사물 |
buporopion |
CYP2B6 |
hydroxybupropion |
C1237
[13C6]-Hydroxybupropion hydrochloride salt |
C1412
[2H9]-Hydroxybupropion hydrochloride salt |
C3290
[2H8]-Hydroxybupropion hydrochloride salt |
C7470
(S)-Hydroxybupropion |
C7471
(R)-Hydroxybupropion |
diclofenac |
CYP2C9 |
4-hydroxydiclofenac |
C857
[13C6]-Diclofenac |
C545
[2H4]-4'-Hydroxydiclofenac |
C2654 Diclofenac
sodium salt |
C1238
[13C6]-4'-Hydroxydiclofenac |
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C2854
4'-Hydroxydiclofenac |
S-mephenytion |
CYP2C19 |
4-hydroxy-s-mephenotine |
C3044
[2H4]-4-Hydroxymephenytoin |
C2504
4-Hydroxymephenytoin |
chlozoxazone |
CYP2E1 |
6-hydroxychlozoxazone |
C1261
[13C6]-6-Hydroxychlorzoxazone |
felodipine |
CYP3A |
dehydrofelodipine |
C5117 Felodipine |
C409
[13C4]-Dehydrofelodipine |
C3067
[2H3]-Felodipine |
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C412
[13C,2H3]-Felodipine |
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C416
[13C5,2H3]-Felodipine |
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coumarin |
CYP2A6 |
7-hydroxycoumarin |
C563
[2H5]-7-Hydroxycoumarin |
C3551 Diprophylline |
tolbufamide |
CYP2C9 |
hydroxymethyltolbufamide |
C517
[2H14]-5-Hydroxymethyltolterodine, racemic mixture |
C1212
5-Hydroxymethyltolterodine formate salt |
dextromethorphan |
CYP2D6 |
dextrophan |
C1579
[13C,2H3]-Dextromethorphan hydrobromide salt |
C536
[2H3]-Dextromethorphan hydrobromide salt |
testosterone |
CYP3A |
6beta-hydroxytestosterone |
C2675 Testosterone |
C1314
[2H4]-6-β-Hydroxytestosterone |
C2152
[2H4]-Testosterone |
C3429
[2H6]-6-β-Hydroxytestosterone |
C2154
[2H5]-Testosterone |
C2826
6-β-Hydroxytestosterone |
C2502
[2H3]-Testosterone |
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C3438
[2H8]-Testosterone |
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midazolam |
CYP3A |
1'-Hydroxymidazolam |
C1240
[13C6]-1-Hydroxymidazolam |
C3415
1-Hydroxymidazolam |
4'-Hydroxymidazolam |
C4185
[13C6]-4-Hydroxymidazolam |
C5451
4-Hydroxymidazolam |